Vaccine and Treatment Information

Vaccine and Treatment Information

There are currently two vaccines approved under FDA Emergency Use Authorization for mpox:

  • JYNNEOS is a two-dose vaccine given 28 days apart and takes 2 weeks from the second dose for peak immunity to develop.
  • ACAM2000 is a single dose vaccine that takes 1 month after vaccination for peak immunity to develop and is an alternative to JYNNEOS.

Your healthcare provider will help determine the best option for you based on your health history, risk factors, and time of exposure (if one occurred).


Who can get vaccinated?

  • Gay, bisexual, or other men who have sex with men and/or transgender, gender non-conforming, non-binary people.
  • People who are at least 18 years old.
  • People who have had multiple or anonymous sex partners in the last 2 weeks.
  • Laboratory and healthcare workers.
  • People who have had contact with someone who has monkeypox.

These vaccines are being used as post-exposure prophylaxis (PEP) within 4 days after exposure, post-exposure prophylaxis (PEP)++ for those with high risk factors that make them more likely to get mpox, and pre-exposure prophylaxis (PrEP) for those with high risk for exposure. There is currently limited supply of these vaccines, so if you are in one of these categories and/or may have been exposed, please contact your healthcare provider.


If you have been exposed to mpox virus or have any symptoms, please contact your healthcare provider as soon as possible as there is treatment available.